POPULÆRVITENSKAP
Med tanke på at det finnes ti mikroorganismer for hver eneste celle i kroppen vår, gir vi mikrobene lite oppmerksomhet. Ved å tilrettelegge for mangfold av mikrober i kroppen vår, mener jeg vi vil bli bedre beskyttet mot sykdommer, skriver Gro Vatne Røsland. (Foto: Shutterstock / NTB)
Vern om dine mikrober om du vil unngå sykdom
POPULÆRVITENSKAP: En viktig nøkkel for bedre helse og velvære ligger i vår hjelpsomme og uvurderlige hær av mikrober. Feil kosthold og overforbruk av antibiotika kan påvirke kroppens mikrobiota betydelig.
Gro Vatne RøslandPH.D. I BIOMEDISIN
Mandag 25. januar 2021 – 11:18
Vårt kanskje viktigste våpen i kampen mot sykdommer er mikrobiota. Mikrobiota er samlingen av alle mikroorganismer, som bakterier, virus og sopp, som lever på indre og ytre overflater på kroppen.
Betydningen av mikrobene som lever i kroppen vår er omfangsrik og avgjørende for balansert immunforsvar og hormonbalanse. Forskning antyder at mikrobesammensetningen påvirker alt fra tarmfunksjon til personlighet. Både antall og mangfold er avgjørende. Med tanke på at det finnes ti mikroorganismer for hver eneste celle i kroppen vår, gir vi mikrobene lite oppmerksomhet. Et steg mot bedre innsikt i god helse, vil være å anerkjenne nytteverdien av samarbeidet mellom mikrobene og kroppen vår.
Ubalanse kan føre til sykdom
Kroppen vår er et habitat for milliarder av mikroorganismer som er viktige for vår daglige drift. Ved å tilrettelegge for mangfold av mikrober i kroppen vår, mener jeg vi vil bli bedre beskyttet mot sykdommer relatert til mikrobiell ubalanse, også kalt dysbiose. Med en jevn flyt av ny forskning, blir listen av sykdommer relatert til dysbiose lengre og lengre.
ANNONSE
Flere studier viser at det økologiske mangfoldet i tarmen lider som et resultat av forandringer i livsstil. Disse forandringene inkluderer:
- mindre variert kosthold
- mer ferdigmat
- bruk av konserveringsmidler og tilsettingsstoffer
- økt medisinbruk
- mindre fysisk aktivitet
Som resultat av disse faktorene, dør mange av mikrobene ut, og mangfoldet reduseres. Studier har vist at bare ved å fore mus med to av tilsetningsstoffene som vi bruker i produksjon av ferdigmat, ble mangfoldet i tarmfloraen gradvis lavere. Etter 4. generasjon mus, var reduksjonen i tarmfloraen på hele 50 prosent!
Det er urovekkende å se at også kommende generasjoner påvirkes i negativ retning av vår livsstil. Blir mikrobeartene våre tapt, eller om det er mulig å gjenopprette dem? Fremdeles vet vi ikke nok om funksjonen til alle mikrobene og samarbeidet med kroppen.
Får mors mikrober ved fødselen
Allerede fra fødselen starter det viktige samarbeidet mellom deg og mikrobene. I løpet av den lille babyens reise ut av mors kropp, eksponeres den for milliarder av ørsmå beskyttere fra mors sekreter som vil flytte inn i tarmen og komme barnet til nytte. Denne fødselsgaven fra mor er unik, en rustning den lille kan nyte godt av hele sitt liv. Forskning viser at mors mikroflora, både i tarm og vagina forandrer seg før, under og etter fødsel. Vi har lenge visst at vaginal fødsel, er det beste for både mor og barn, men det har vært lite fokus på «mikrobiell svøping» i denne sammenheng.
ANNONSE
Også etter fødselen blir den lille bombardert med mikrober fra omgivelser og hudkontakt. Selv om babyens immunforsvar ennå ikke er fullt utstyrt, og barnet derfor er sårbar for sykdomsfremmende mikrober, er mellommenneskelig nærkontakten viktig for utviklingen av immunforsvaret. Forskning har vist at næringsstoffer produsert av mikrobene, og trolig også noen typer bakterier blir transportert fra mors tarmflora til morsmelk; og videre hvor avgjørende brystmelk er for utvikling av immunforsvaret til babyer. Vi vet at morsmelk er bra for babyen og at dette er forbundet med utvikling av immunforsvaret, men at mikrober direkte overleveres på denne måten, er ny kunnskap.
Hos et friskt barn er det avgjørende at det blir eksponert for mikrober og allergener gjennom hele oppveksten, og det er vist at barn som er oppvokst på gård, med nærkontakt med dyr og jord og dermed et rikt mangfold av mikrober, sjeldnere utvikler allergier.
Vi må ta grep om kosthold og antibiotikabruk
Trolig er forandring i kostholdsvaner den største årsaken til at mange ikke har en optimal tarmflora. Lege og kostholdspesialist Berit Norstrand snakker mye om betydningen av vår mikrobiota og hvordan vi kan ta vare på vare på den. I sitt arbeid fremhever Norstrand at hele 80-90 prosent av våre immunceller befinner seg til enhver tid i tarmveggen, hvor de blir næret, programmert og stabilisert av vår tarmflora.
Dels grunnet manglende kunnskap om konsekvenser, har antibiotika blitt misbrukt i tiår, både i helsesektoren, men også i dyrehold og matproduksjon. Antibiotika fanger bredt, og ofte er dette bra når tiden er kort og sykdommen herjer. Men antibakteriell behandling kan ikke skille mellom sykdomsrelaterte- og nyttige bakterier. Det er kjent at overbehandling med antibiotika kan føre til dysbiose.
I mange tilfeller er det mulig at mat og riktig kosthold kan brukes som medisin for å bedre tarmfunksjon.
Gro Vatne Røsland
Jeg vil nødig oppfattes som motstander, men jeg mener at det er avgjørende at tiltak for å begrense bruk av antibiotika fortsetter. Dette er viktig både med tanke på å hindre utvikling av multiresistente bakterier, men også for å ta bedre vare på vår mikrobiota.
Håpet er at bedre og mer målrettede behandlingsformer for bekjempelse av infeksjonssykdommer utvikles og tas i bruk. Praksis for bruk av antibiotika har på verdensbasis vært lite kontrollert, før fokus på faren for utvikling av multiresistente bakterier fikk oppmerksomhet i begynnelsen av dette århundret. Selv om vi i Norge har begrenset bruk av antibiotika drastisk de senere årene, kan man i flere land i Europa fremdeles få antibiotika over disk, uten resept.
En ny studie utført av forskere ved Universitet i Helsinki viser at tilfeller av pasienter med den aldersrelaterte nevrodegenerative sykdommen Parkinsons´ har økt i forekomst i takt med bruken av antibiotika. Forskerne mener at lenken er knyttet til antibiotika sin påvirkning av tarmflora.
Mat som medisin
Å redusere bruk av antibiotika og annen medisinsk behandling, kan av mange årsaker være utfordrende. Med økt bevissthet rundt dette temaet, både hos lekmenn og medisinsk personell, kan vi ta grep som kan bidra til beskyttelse og gjenoppbygging av tarmfloraen før- under og etter behandling.
Jeg vil dra en av slutningene til Berit Norstrand om mikrobiota og immunsystemet vårt ennå lengre ved å påstå at mikrobene er en av de viktigste komponenter av vårt immunsystem. Immunsystemet blir betydelig svekket som følge av ubalanse i mikrobiota. Vi vet allerede mye om hvordan vi kan tilpasse kostholdet vårt for å fremme balanse i mikrobiota. Små endringer og fokus på mat som nærer mikrobene kan være nok til å gjenskape balanse.
I mange tilfeller er det mulig at mat og riktig kosthold kan brukes som medisin for å bedre tarmfunksjon. Per i dag er det kun medisinsk personell med spesiell interesse for feltet som er bevisst på hvordan man best ivaretar tarmfloraen til sine pasienter. Variert, sundt, fiberrikt kosthold med innslag av fermentert mat er vist å nære mikrobene våre på en god måte. Begrenset bruk av prefabrikkert mat og fokus på å opprettholde normal vekt er også viktig for å opprettholde en balansert mikrobiota.
Mikrobiota må inn i behandling
Personlig tror og håper jeg også at kontrollert overføring av mikrobiota mellom mennesker vil være et høyere prioritert alternativ for behandling av dysbiose i fremtiden.
Utvikling av pre- og probiotika-tilskudd er under utvikling, men vi trenger mer kunnskap om hva som er den beste sammensetningen og hvordan det skal brukes på best måte. Man har fremdeles ikke funnet den «perfekte sammensetning» av en sunn mikrobiota, og forskning tyder på at den nok er individuell. Jeg mener at ved å inkludere kunnskap om mikrobiota i Folkehelseinstituttets retningslinjer og i medisinsk utdannelse, kan det kanskje bli lettere for behandlende personell å være bevisst på denne problemstillingen.
Det er både et samfunnsansvar og et privilegium å ta vare på egen helse, og det er liten tvil om at med mer kunnskap og større fokus på mikrobiota og bruken av antibiotika vil folkehelsen bli bedre. Bedre folkehelse = lavere helseutgifter for samfunnet. Jeg slår herved et slag for våre små venner. Jeg håper vi som folk og samfunn vil bli bedre til å ta vare på helsen ved å bli mer bevisst på hvordan i kan bygge opp og ta vare på vår mikrobiota.
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There are actually a number of details like that to take into consideration. That may be a nice point to deliver up. I offer the thoughts above as general inspiration but clearly there are questions just like the one you convey up the place the most important thing will probably be working in honest good faith. I don?t know if best practices have emerged round things like that, however I am sure that your job is clearly identified as a good game. Both boys and girls feel the affect of just a moment?s pleasure, for the rest of their lives.
Thanks for your post. One other thing is the fact individual states in the United states of america have their own laws which affect homeowners, which makes it extremely tough for the our elected representatives to come up with the latest set of recommendations concerning foreclosed on house owners. The problem is that a state features own laws which may have impact in an undesirable manner on the subject of foreclosure procedures.
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Most of whatever you say is supprisingly legitimate and it makes me wonder the reason why I had not looked at this in this light previously. This particular article truly did turn the light on for me as far as this particular issue goes. Nevertheless there is just one issue I am not too cozy with and while I try to reconcile that with the main theme of the point, permit me see what the rest of your readers have to point out.Well done.
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I have observed that in the world the present moment, video games would be the latest popularity with kids of all ages. There are occassions when it may be difficult to drag your family away from the video games. If you want the best of both worlds, there are plenty of educational games for kids. Good post.
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Do you mind if I quote a few of your articles as long as I provide credit and sources back to your webpage? My blog site is in the exact same area of interest as yours and my users would really benefit from some of the information you present here. Please let me know if this okay with you. Appreciate it!
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The very next time I read a blog, Hopefully it doesn’t fail me just as much as this particular one. After all, I know it was my choice to read through, however I genuinely believed you’d have something useful to say. All I hear is a bunch of moaning about something you can fix if you were not too busy looking for attention.
Thanks for the various tips provided on this web site. I have noticed that many insurance agencies offer consumers generous savings if they choose to insure many cars with them. A significant number of households currently have several automobiles these days, specially those with elderly teenage kids still residing at home, plus the savings in policies can soon increase. So it is a good idea to look for a great deal.
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Through my research, shopping for electronic products online can for sure be expensive, nevertheless there are some tips and tricks that you can use to acquire the best discounts. There are continually ways to locate discount deals that could help to make one to possess the best electronics products at the lowest prices. Interesting blog post.
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When I initially commented I clicked the “Notify me when new comments are added” checkbox and now each time a comment is added I get three e-mails with the same comment. Is there any way you can remove me from that service? Thanks a lot!
Nice read, I just passed this onto a colleague who was doing a little research on that. And he just bought me lunch as I found it for him smile Therefore let me rephrase that: Thank you for lunch!
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One more thing I would like to talk about is that rather than trying to fit all your online degree tutorials on days that you end work (since most people are fatigued when they return), try to find most of your instructional classes on the weekends and only a couple courses in weekdays, even if it means taking some time away from your saturdays. This pays off because on the week-ends, you will be extra rested and also concentrated with school work. Many thanks for the different ideas I have learned from your blog.
I do agree with all of the ideas you’ve presented in your post. They’re very convincing and will definitely work. Still, the posts are very short for beginners. Could you please extend them a little from next time? Thanks for the post.
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Hello there! I know this is kinda off topic but I was wondering if you knew where I could get a captcha plugin for my comment form? I’m using the same blog platform as yours and I’m having problems finding one? Thanks a lot!
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